Curriculum
Vitae
RESARCH
INTERESTS:
My research
interests are computed tomography algorithms, quantitative SPECT/PET imaging, quantitative imaging methods for internal
dosimetry, Monte Carlo simulation, small animal imaging (microCT, microPET, and
microSPECT), and multi-modality imaging.
EMPLOYMENT:
|
Title |
Year |
Institution |
Department |
|
Research
Associate |
2008.9-Present |
Johns
|
Radiology |
|
Postdoctoral
Fellowship |
2006.9-2008.8 |
Johns
|
Radiology |
|
Research
Assistant |
2002.9-2006.8 |
Johns
|
Radiology |
|
Research
Assistant |
2001.9-2002.8 |
|
Biomedical
Engineering |
|
Research
Assistant |
1997.9-2001.8 |
|
Engineering
Physics |
EDUCATION
and TRAINING:
|
Degree |
Year |
Institution |
Discipline |
|
Postdoctoral
Training |
2006-2008 |
Johns
|
Radiology |
|
Ph.D. |
2002-2006 |
|
Environmental
Health Sci. * |
|
|
2001-2002 |
|
Biomedical
Engineering |
|
M.S. |
1998-2001 |
|
Engineering
Physics |
|
B.S. |
1996-1998 |
|
Enterprises
Management |
|
B.S. |
1994-1998 |
|
Engineering
Physics |
* Concentrated in
Radiation Health Sciences
RESEARCH
EXPERIENCE:
Johns
Division of Medical Imaging Physics, Department of
Radiology
Medical Imaging Research Lab
Medical Imaging Research Lab, Department of
Engineering Physics
OTHER
EXPERIENCE:
AWARDS and
HONORS:
Title: Comparison and Validation of Conjugated View
Planar, Model-Based Quantitative Planar, and Quantitative SPECT Methods for
Whole Organ Activity Estimation
Title: Comparison of Conventional Planar, Quantitative
Planar, Quantitative SPECT, and Combined Planar-Spect Organ Residence Time
Estimation Methods for Targeted Radionuclide Therapy Dosimetry
PROFESSIONAL
ACTIVITIES
EXTRACURRICULAR
ACTIVITIES
Refereed Scientific Articles
1.
Sgouros
G, Frey EC, Wahl RL, He B,
2.
He B, Wahl RL, Du Y, Sgorous G, Jacene H, Flinn I and Frey EC. Comparison
of Residence Time Estimation Methods for Radioimmunotherapy Dosimetry and
Treatment Planning - Monte Carlo Simulation Studies. IEEE Trans. Med. Img. 27(4): 521-530, 2008.
3.
Prideaux
AR, Song H, Hobbs RF, He B, Frey EC,
Ladenson PW, Wahl RL, Sgouros G. Three-Dimensional
Radiobiological Dosimetry (3D-RD): Application of Radiobiological Modeling to
Patient-Specific, 3-D Imaging-based Internal Dosimetry. J. Nucl. Med. 48:
1008-1016, 2007.
4.
Song
H, He B, Prideaux AR, Du Y, Frey EC,
Kasecamp W, Ladenson PW, Wahl RL and Sgouros G. Lung
Dosimetry for Radioiodine Therapy Treatment Planning in the Case of Diffuse
Lung Metastases. J. Nucl. Med. 47: 1985-1994, 2006.
5.
He B and Frey EC. Comparison of
conventional, model-based quantitative planar, and quantitative SPECT image
processing methods for organ activity estimation using In-111 agents. Phys
Med Biol, 51(2006): 3967-3981, 2006.
6.
He B, Du Y, Song X, Segars WP and Frey EC. A Monte Carlo and
physical phantom evaluation of quantitative In 111 SPECT. Phys Med Biol,
50(2005): 4169-4185, 2005.
7.
He B, Jin Yongjie, and Li Yulan. Defining
Nuclear Medical File Formal Based on DICOM Standard. Nuclear Electronics
& Detection Technology. 21(6): 440-443, 2001. (In Chinese)
8.
He B and Jin Yongjie. DICOM Medical Image File Format.
International Medical Devices. 7(1): 14-19, 2001. (In Chinese)
Articles Under Review
1.
He B, Wahl RL, Sgorous G, Du Y, Jacene H, Flinn I, Hammes
RJ, Bianco J, Kahl B and Frey EC.
Comparison of Residence Time Estimation Methods for Radioimmunotherapy
Dosimetry and Treatment Planning - Patient Studies.
2.
He B, Du Y, W. Paul Segars, Wahl RL, Sgorous G, Jacene H, and Frey EC. Evaluation of quantitative imaging methods
for ibritumomab tiuxetan dosimetry using a population of phantoms having
realistic variations in anatomy and uptake.
Published Abstracts & Conference Proceeding
1.
He B and Frey EC. Is Long Planar Imaging Time Necessary for
Targeted Radionuclide Therapy Treatment Planning? J Nucl Med. 49: 281p, 2008.
2.
Song
N, He B, Du Y, and Frey EC. Evaluation of
Accuracy and Precision of Organ Activity Estimates from Quantitative I-131
SPECT. J Nucl Med. 49: 153p, 2008.
3.
Wahl RL, Flinn IW, He B, Kahl B, Frey EC, Rogers K, Jung,
M, Jacene H, and Swinnen L. SPECT-CT/organ
dosimetry: Phase I dose-escalation trial of yttrium 90 ibritumomab tiuxetan
(90Y-RIT) with stem cell transplantation (ASCT) in NHL. J Nucl Med. 49: 144p, 2008.
4.
He B, Du Y, and Frey EC. Quantitative SPECT Imaging Methods on Tumor
Activity Quantification - A Monte Carlo Simulation Study. The 2007 Nuclear
Science Symposium and Medical Imaging Conference.
5.
He B and Frey EC. The Impact of VOI Definition on Activity
Estimation Accuracy in Quantitative SPECT and Planar Imaging Methods. The 2007
Nuclear Science Symposium and Medical Imaging Conference.
6.
Du Y, He B, and Frey EC. Quantitative
Reconstruction Using Combined Voxel and Volume-of-Interest Models Obtained from
High-Resolution Anatomical Images. The 2007 Nuclear Science Symposium and
Medical Imaging Conference.
7.
Song
N, He B, and Frey EC. Investigation of
Effects of Volume-of-Interest Mis-registration on Accuracy of Organ Activity
Estimates obtained with Quantitative Planar Processing. The 2007 Nuclear
Science Symposium and Medical Imaging Conference.
8.
Bading
JR, He B, Zhan J, Williams LE, and
Frey EC. Quantitative SPECT with In-111: Comparison of collimators with
different resolution and sensitivity. J Nucl Med. 48: 421p, 2007.
9.
Frey
EC, He B, Sgorous G, Flinn I and
Wahl RL. Development
and validation of an organ residence time estimation method for high dose Y-90
ibritumomab tiuxetan therapy. E J Nucl Med. 33(2): S103-S103, 2006.
10. He
B and Frey EC. Evaluation
of Quantitative Imaging Methods for Ibritumomab Tiuxetan Dosimetry Using a
Population of Phantoms Having Realistic Variations in Anatomy and Uptake. J
Nucl Med. 47(5): 155p- 155p, 2006.
11. Frey EC, He B, Sgorous G, Flinn I and Wahl RL. Estimation of Post-therapy
Marrow Dose Rate in Myeloablative Y-90 Ibritumomab Tiuxetan Therapy. J Nucl
Med. 47(5): 156p-156p, 2006.
12. Du Y,
He B, Wahl RL and Frey EC. Model-based Downscatter Estimation in
Simultaneous I-131/In-111 Dual-isotope SPECT imaging. J Nucl Med. 47(5):
196p-197p, 2006.
13. He
B, Frey EC and Segars WP.
Evaluation of a New Method for Absolute in vivo Quantitation of Tumor and Organ
Activity from Conjugate View Planar Images. The 2005 Nuclear Science Symposium
and Medical Imaging Conference.
14. He
B, Frey EC and Tsui BMW.
Comparison and Validation of Conjugated View Planar, Model-Based Quantitative
Planar, and Quantitative SPECT Methods for Whole Organ Activity Estimation. J
Nucl Med. 46(5): 26p-26p, 2005.
15. He
B, Frey EC, Sgorous G,
Flinn I and Wahl RL. Comparison of Conventional Planar, Quantitative Planar,
Quantitative SPECT, and Combined Planar-Spect Organ Residence Time Estimation
Methods for Targeted Radionuclide Therapy Dosimetry. J Nucl Med. 46(5):
51p-51p, 2005.
16. Song H, Sgorous G, Frey EC, Kasecamp W, He B, Du Y, Ladenson PW and Wahl RL.
Treatment planning for I-131 therapy of a patient with metastatic thyroid
cancer to lungs using the Monte Carlo MCNP4b packaging and 3D-ID. J Nucl Med.
46(5): 193p-193p, 2005.
17. He
B, Frey EC, Tsui BMW.
Comparison of Conventional and Model-Based Quantitative Planar Image Processing
Methods for Organ Activity Estimation Using In-111 Agents. The 2004 Nuclear
Science Symposium and Medical Imaging Conference.
18. He
B, Frey EC, Du Y, Song X,
Segars WP and Tsui BMW. A Monte Carlo and Physical Phantom Evaluation of the
Quantitative SPECT for In-111. J Nucl Med. 45: 47p-47p, 2004.
19. Frey EC, He B, Sgorous G, Flinn I, , Segars WP, Wahl RL and Tsui BMW.
Comparison of Conventional Planar, Quantitative Planar, Quantitative SPECT, And
Combined Planar-SPECT Organ Residence Time Estimation Methods for Targeted
Radionuclide Therapy Dosimetry. J Nucl Med. 45: 46p-46p, 2004.
20. He
B, Frey EC, Beck TJ,
Sawyer SA and Tsui BMW. Measurement
and Deconvolution of Glare in a Micro-CT Scanner for In-Vivo Small Animal
Imaging. Conference Record of the 2003 Nuclear Science Symposium and
Medical Imaging Conference.
21. Sawyer SA, Frey EC, He B, Wang Y and Tsui BMW. Implementation
of Short Scan Reconstruction with Compensation for Geometric Alignment for a
Micro-CT System. Conference Record of the 2003 Nuclear Science Symposium
and Medical Imaging Conference.
Books
1.
He B, Ma T, Wang Y and Zhu H. Visual C++ Digital Image
Processing (Second Edition). People Posts and Telecommunications Publishing
House, P. R. China. ISBN 7-115-10955. 2002. (In Chinese)
2.
He B, Ma T, Wang Y and Zhu H. Visual C++ Digital Image
Processing. People Posts and Telecommunications Publishing House, P. R. China.
ISBN 7-115-09263. 2001. (In Chinese)
3.
He B and Wang Y. Visual J++ Applied Programming
Techniques. People Posts and Telecommunications Publishing House, P. R. China.
ISBN 7-115-08123. 1999. (In Chinese)
4.
He B, Wang Y, Feng F and Liu X. Visual Basic 6.0
Application Guide. People Posts and Telecommunications Publishing House, P. R.
China. ISBN 7-115-07516. 1998. (In Chinese)